Calorie reduction

Recently I'm interested in the opinion that the 30% reduction of required calorie prevents aging, finding out the eyeopening article below.

"At one time, scientists believed aging to be not just deterioration but an active continuation of an organism's genetically programmed development. Once an individual achieved maturity, "aging genes" began to direct its progress toward the grave. This idea has been discredited, and conventional wisdom now holds that aging really is just wearing out over time because the body's normal maintenance and repair mechanisms simply wane. Evolutionary natural selection, the logic goes, has no reason to keep them working once an organism has passed its reproductive age.

However, recent research by D. A. Sinclair and L. Guarente showed that a handful of genes that control the body's defenses during hard times can also dramatically improve health and prolong life in diverse organisms. Sirtuins are responsible genes and the gene products are NAD-dependent histon deacetylase thus activating histon to keep cells young. Understanding how they work may reveal the keys to extending human life span while banishing diseases of old age.　(D.A.Sinclair & L.Guarente: Scientific American, March 2006)

http://members.jcom.home.ne.jp/kisono/sirtuin/sirtuin.html"


An admirable man Mr. Hosokawa in Kyusyu who is a former Prime minister of Japan tries to eat less than 60% of ordinal required calorie.

Various information around me forces to follow some way to calorie reduction, do I try it?